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Hormone Imbalance Symptoms You Shouldn't Ignore

PBTT

Private Blood Tests Team

Clinical Team

29 Dec 202510 min read

Hormones are chemical messengers that control virtually every process in your body. From regulating your metabolism and energy levels to influencing your mood, sleep, fertility, and weight, hormones work behind the scenes to keep everything running smoothly. When hormone levels become imbalanced, the effects can be far-reaching and significantly impact your quality of life.

Many people live with hormone imbalance symptoms for years, attributing them to stress, ageing, or simply "how things are." However, recognising these symptoms and seeking appropriate testing can lead to treatments that dramatically improve how you feel.

Understanding Hormones and Their Functions

Your body produces dozens of hormones, each with specific roles. The major hormones that commonly become imbalanced include:

  • Thyroid hormones (T3, T4) — Control metabolism and energy
  • Cortisol — The stress hormone
  • Insulin — Regulates blood sugar
  • Oestrogen and progesterone — Female sex hormones
  • Testosterone — Present in both sexes, higher in men
  • DHEA — A precursor to sex hormones
  • Growth hormone — Affects body composition and metabolism
  • Melatonin — Regulates sleep
  • When any of these hormones are too high or too low, symptoms can develop that affect multiple body systems.

    Symptoms You Should Not Ignore

    ### 1. Persistent Fatigue

    Feeling exhausted despite getting enough sleep is one of the most common signs of hormone imbalance. Multiple hormones can cause fatigue when imbalanced:

  • Low thyroid hormones cause profound tiredness and sluggishness
  • High or low cortisol disrupts energy regulation
  • Low testosterone (in both men and women) reduces vitality
  • Insulin resistance causes energy crashes
  • If you are constantly tired and rest does not help, hormone testing should be considered.

    ### 2. Unexplained Weight Changes

    Gaining or losing weight without changes to your diet or exercise routine often points to hormonal issues:

  • Hypothyroidism (underactive thyroid) causes weight gain
  • Hyperthyroidism (overactive thyroid) causes weight loss
  • High cortisol promotes abdominal fat storage
  • Insulin resistance makes weight loss extremely difficult
  • Low oestrogen (during menopause) changes fat distribution
  • For more information about thyroid-related symptoms, read our article on whether low thyroid can cause headaches.

    ### 3. Mood Changes and Mental Health Symptoms

    Hormones profoundly affect brain chemistry and mood. Symptoms to watch for include:

  • Depression or persistent low mood
  • Anxiety and nervousness
  • Irritability and mood swings
  • Brain fog and difficulty concentrating
  • Memory problems
  • These symptoms can result from thyroid imbalances, cortisol dysregulation, sex hormone changes, or combinations of hormonal issues. Learn more about stress hormones in our article on the link between stress, cortisol, and your blood test results.

    ### 4. Sleep Problems

    Hormones regulate your sleep-wake cycle, and imbalances can cause:

  • Difficulty falling asleep
  • Waking during the night
  • Waking too early
  • Unrefreshing sleep despite adequate hours
  • Cortisol should be low at night; elevated evening cortisol disrupts sleep. Melatonin, oestrogen, progesterone, and thyroid hormones also affect sleep quality.

    ### 5. Changes in Skin, Hair, and Nails

    Your appearance often reflects your hormonal health:

  • Dry skin and hair — Common with hypothyroidism
  • Hair loss or thinning — Thyroid disorders, low iron, hormonal changes
  • Acne in adults — Often related to androgen excess or imbalance
  • Brittle nails — May indicate thyroid problems
  • Excessive hair growth (hirsutism) — Can indicate PCOS or adrenal issues
  • ### 6. Irregular Periods or Fertility Issues

    For women, menstrual irregularities are often the first sign of hormone imbalance:

  • Irregular, absent, or very heavy periods
  • Severe PMS or PMDD
  • Difficulty conceiving
  • Painful periods
  • These symptoms may indicate polycystic ovary syndrome (PCOS), thyroid disorders, elevated prolactin, or imbalances in oestrogen and progesterone.

    ### 7. Low Libido

    Reduced sex drive affects both men and women and can result from:

  • Low testosterone (in both sexes)
  • Low oestrogen (particularly during perimenopause and menopause)
  • High prolactin
  • Thyroid disorders
  • Chronic stress and elevated cortisol
  • ### 8. Hot Flushes and Night Sweats

    While commonly associated with menopause, these symptoms can occur at any age and may indicate:

  • Declining oestrogen levels
  • Thyroid dysfunction
  • Adrenal issues
  • Other hormonal imbalances
  • ### 9. Muscle Weakness and Joint Pain

    Hormones affect musculoskeletal health:

  • Low thyroid causes muscle aches and weakness
  • Low testosterone reduces muscle mass and strength
  • High cortisol breaks down muscle tissue
  • Vitamin D deficiency (technically a hormone) causes muscle pain
  • ### 10. Digestive Issues

    Hormones influence gut function, and imbalances can cause:

  • Constipation (common with hypothyroidism)
  • Diarrhoea (can occur with hyperthyroidism)
  • Bloating
  • Changes in appetite
  • Testing for Hormone Imbalances

    If you recognise several of these symptoms, blood testing can identify whether hormonal imbalances are the cause. Key tests include:

    Thyroid panel:

  • TSH, Free T4, Free T3, thyroid antibodies
  • Stress and adrenal hormones:

  • Cortisol (morning), DHEA-S
  • Sex hormones:

  • Oestrogen, progesterone, testosterone, SHBG, FSH, LH
  • Metabolic hormones:

  • Fasting insulin, HbA1c
  • Other important markers:

  • Vitamin D, iron studies, B12
  • For a comprehensive overview of health testing, read our guide to what's included in a comprehensive health check.

    When to Seek Help

    Do not dismiss persistent symptoms as "normal" or simply part of ageing. Seek testing if you experience:

  • Multiple symptoms from this list
  • Symptoms that interfere with daily life
  • Symptoms that have developed or worsened recently
  • Symptoms that do not improve with lifestyle changes
  • Many hormone imbalances are easily treatable once identified, often with dramatic improvements in quality of life.

    Hormone Testing in London

    At Private Blood Tests London, we offer comprehensive hormone testing at our CQC-registered clinic in South Kensington. From thyroid panels to full hormone profiles, our experienced healthcare team can help identify imbalances and guide you toward appropriate treatment.

    Explore our [thyroid tests](/thyroid-test) and [comprehensive health screening packages](/health-screening).

    Stop accepting symptoms that diminish your quality of life. Book your hormone blood test today and take the first step toward feeling like yourself again.

    Ready to Book Your Test?

    Visit our CQC-registered clinic in South Kensington for professional blood testing services.