What Is Ovarian Cancer Screening and Why Does It Matter?
Ovarian cancer screening refers to the use of specific blood tests and biomarker assessments designed to detect early biological indicators that may be associated with ovarian cancer risk. Early screening matters because ovarian cancer is often identified at later stages, when outcomes can be more complex. Proactive blood testing can help individuals understand their personal risk profile and seek timely medical advice.
In the UK, ovarian cancer affects approximately 7,500 women each year, according to Cancer Research UK. Despite being one of the most common cancers in women, there is currently no national screening programme for ovarian cancer, which makes private ovarian cancer screening an increasingly important option for those who wish to take a proactive approach to their health. At Private Blood Tests London, our nurse-led clinic offers convenient biomarker blood testing in central London, helping individuals gain valuable health insights. For a broader overview of how blood testing relates to cancer risk, our guide on whether blood tests can detect cancer may be helpful.
Understanding your ovarian cancer risk through early screening may provide peace of mind, highlight areas that warrant further medical attention, or simply give you a clearer picture of your current wellbeing.
Practical Insight: Ovarian cancer screening blood tests do not diagnose cancer. They measure specific biomarkers that may indicate the need for further investigation with an appropriate healthcare professional.
Who Should Consider Ovarian Cancer Risk Screening?
Not everyone faces the same level of risk. Certain factors may increase an individual’s likelihood of developing ovarian cancer, and understanding these factors can help inform your decision about whether screening is appropriate for you.
Key Risk Factors to Be Aware Of
Practical Insight: Having one or more risk factors does not mean you will develop ovarian cancer. It simply means that staying informed through periodic blood testing can be a sensible part of your overall health management approach.
Understanding the CA-125 Biomarker
The most widely recognised blood test associated with ovarian cancer screening is the CA-125 test. CA-125 (Cancer Antigen 125) is a protein found on the surface of many ovarian cancer cells. Elevated levels of CA-125 in the blood can sometimes highlight the need for further clinical investigation.
What Does the CA-125 Blood Test Measure?
The CA-125 test measures the concentration of this protein in a blood sample. A result is typically reported in units per millilitre (U/mL).
| **CA-125 Level** | **What It May Suggest** |
|---|---|
| Below 35 U/mL | Generally considered within the normal range for most individuals |
| 35–65 U/mL | May indicate mildly elevated levels; can be associated with non-cancerous conditions such as endometriosis, fibroids, or pelvic inflammatory disease |
| Above 65 U/mL | May warrant further medical investigation; healthcare professionals typically recommend additional assessment |
It is essential to understand that CA-125 levels can be elevated for many reasons that are unrelated to cancer. Menstruation, pregnancy, liver disease, and certain infections can all influence results.
Practical Insight: A single elevated CA-125 result does not constitute a diagnosis. It is one piece of information that, when combined with personal history and clinical assessment, can help guide next steps.
How Often Should You Consider Ovarian Cancer Screening?
The frequency of ovarian cancer risk screening depends on your individual circumstances:
Practical Insight: Keeping a personal health record of your screening results over time can be a valuable resource for any healthcare professional you consult.
What Do Your Ovarian Cancer Screening Results Mean?
Normal Range Results
A result within the normal reference range is generally reassuring. It suggests that your CA-125 levels are not currently elevated. However, normal results do not guarantee the absence of disease, and routine monitoring remains advisable for those with ongoing risk factors.
Elevated Results
An elevated CA-125 result can understandably cause concern. It is important to remember that elevation can suggest a variety of conditions — many of which are benign. If your result is elevated, we recommend:
1. Discussing your results with an appropriate healthcare professional
2. Providing context about your symptoms, family history, and general health
3. Considering repeat testing after an interval, as levels may fluctuate naturally
For those interested in a broader assessment, our article on the hidden role of blood tests in fertility and hormone health can complement ovarian cancer biomarker testing with useful context on reproductive health markers.
Ovarian Cancer Screening in London: NHS vs Private Testing
| **Factor** | **NHS Pathway** | **Private Blood Testing** |
|---|---|---|
| Availability | CA-125 may be requested by GP if symptoms are present | Available on request without requiring a GP referral |
| Waiting Time | May involve waiting for a GP appointment and results | Typically faster appointment booking and turnaround |
| Cost | Free at the point of care | A fee applies; check our website for current pricing |
| Scope | Usually symptom-driven | Can be used proactively for health monitoring |
| Location | Local GP surgery or NHS hospital | Central London clinic |
Practical Insight: Private blood testing and NHS services are not mutually exclusive. Many individuals use private screening to complement their NHS healthcare.
Symptoms That May Prompt Ovarian Cancer Screening
While early-stage ovarian cancer may not always present noticeable symptoms, the following signs — particularly when they are persistent, frequent, or unusual for you — may be worth discussing with a healthcare professional:
Frequently Asked Questions
What is ovarian cancer screening?
Ovarian cancer screening involves blood tests that measure specific biomarkers, most commonly CA-125, which may be associated with ovarian cancer risk. Screening does not diagnose cancer but can highlight the need for further investigation.
Who should consider ovarian cancer risk testing?
Women with a family history of ovarian or breast cancer, those over 50, individuals with BRCA gene mutations, or anyone experiencing persistent unexplained symptoms may wish to consider screening.
How accurate is the CA-125 blood test?
The CA-125 test is a widely used biomarker but is not definitive on its own. Elevated levels can be caused by non-cancerous conditions. Results should be considered alongside personal history and clinical assessment.
Can I get ovarian cancer screening without a GP referral?
Yes. At Private Blood Tests London, you can book a CA-125 blood test directly without needing a GP referral. Browse our full range of available blood tests to find the option that suits you.
How often should I have an ovarian cancer screening blood test?
Frequency depends on your individual risk profile. Women at average risk may consider annual or biennial testing, while those with higher risk factors may benefit from more frequent monitoring.
What happens if my CA-125 result is elevated?
An elevated result does not confirm a diagnosis. It may indicate a range of conditions, some of which are benign. We recommend discussing elevated results with an appropriate healthcare professional.
Is ovarian cancer screening available on the NHS?
There is currently no national NHS screening programme for ovarian cancer. GPs may request a CA-125 test if specific symptoms are present. Private ovarian cancer screening provides an alternative for proactive monitoring.
Does Private Blood Tests London diagnose ovarian cancer?
No. Our nurse-led clinic provides blood testing and reporting only. We do not offer diagnosis, treatment, or prescriptions.
Taking a Proactive Approach to Your Health
Understanding your ovarian cancer risk through early screening is a thoughtful, empowering step. At Private Blood Tests London, our experienced, nurse-led team is here to make the testing process straightforward, comfortable, and accessible. Explore our health screening packages to get started.
*This article is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Private Blood Tests London is a nurse-led screening service. We do not provide GP services, medical consultations, treatment, or prescriptions. If your results indicate areas of concern, please consult your GP or an appropriate healthcare professional.*
*Written: 20 March 2026 | Review date: 20 March 2027*